Nicotinamide peptide NAD+ 500/1000 mg

What is NAD+?

Nicotinamide adenine dinucleotide (NAD) is a vital component of the metabolic processes and reactions that occur in human cells. NAD is crucial to numerous cellular events. These include glycolysis (the breakdown of glucose into pyruvate and hydrogen), the citric acid cycle (the release of stored energy from carbohydrates, proteins and fats through the oxidation of acetyl-CoA), the breakdown of fatty acids, DNA repair and inflammatory responses, to name just a few. These processes cannot take place without NAD. Because it is involved in the body's metabolic processes, NAD undergoes oxidation or reduction, with the oxidised form known as NAD+.

How is NAD+ synthesised?

There are two main mechanisms through which the human body synthesises NAD+. The kynurenine pathway is a pathway in which NAD+ is synthesised from the essential amino acid tryptophan. Enzymes such as tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) facilitate the oxidative breakdown of tryptophan to form formylkynurenine in this pathway. Several enzymatic reactions occur after formylkynurenine is formed, and it is then converted into NAD+ by various enzymes, including 3-hydroxyanthranilic acid 3,4-dioxygenase (3-HAAO).

The second pathway, known as the salvage pathway, recycles NAD+ during the consumption of nicotinic acid, nicotinamide adenine mononucleotide and nicotinamide. The enzyme nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide into nicotinamide adenine mononucleotide (NMN), which is then converted into NAD+ by another enzyme called nicotinamide mononucleotide adenylyltransferase (Nmnat). In addition, nicotinic acid can be a precursor for NAD+ synthesis, generating nicotinic acid mononucleotide (NAMN), which is conjugated with NAD+ by the enzyme Nampt. The availability of multiple pathways for NAD+ synthesis highlights its critical importance in the human body.

Benefits of intravenous NAD therapy

NAD+ plays an important role in all the body's major processes. It is therefore important to maintain optimal NAD+ levels. Signs of NAD+ deficiency, such as pellagra, which presents as dermatitis, dementia or diarrhoea, may require supplemental intravenous NAD therapy. In addition to signs of NAD+ deficiency, there are other reasons why a person may consider receiving an intravenous NAD+ supplement. These may include the following:

Addiction treatment

IV NAD+ therapy is often used to assist in addiction treatment. Patients withdrawing from opioid, alcohol, chemical or prescription drug dependence may benefit from IV NAD+ therapy because it may help alleviate the severity of withdrawal symptoms and reduce drug cravings. Although the mechanism through which NAD+ works in this capacity is still being studied, IV NAD+ is thought to help remove drugs from the body.

Improved cognitive function

As mentioned earlier, NAD+ has been found to have both protective and stimulating effects on the brain. IV NAD+ therapy may therefore be used to potentially improve memory, increase concentration and attention, support brain regeneration and improve overall neurological function. The precise mechanism through which IV NAD+ produces these effects is still being examined in ongoing research.

Chronic fatigue

IV NAD+ therapy has been used to treat people with chronic fatigue and low energy levels. NAD+ is an important cofactor in the glycolytic and tricarboxylic acid pathways, which are responsible for producing adenosine triphosphate (ATP), the primary source of energy in the human body. When NAD+ supplements are administered, ATP production increases, which may lead to improved energy levels and reduced fatigue.

Athletic performance

IV NAD+ therapy has been used by athletes to improve their athletic performance because of its role in ATP production. Intravenously administered NAD+ supplements may increase energy levels, improve cognitive function and improve reaction time during competitions or sporting events. In addition, research suggests that NAD+ supplements may support muscle development and recovery, which may lead to muscle hypertrophy and hyperplasia.

Pain management

IV NAD+ therapy is being studied as a potential way to treat pain because of its anti-inflammatory effect on the body. Inflammation and pain go hand in hand, and the use of NAD+ may help reduce inflammation and provide some relief. Although research is continuing, the effectiveness of NAD+ as a method of pain management has not yet been established.

Use:

1. Initial phase (loading)

• Dosage: 500-1000 mg NAD+

• Infusion duration: 2-4 hours

• Frequency: once a week

NAD+ IV therapy from NAD is an innovative approach to supporting health and slowing the ageing process. Before starting therapy, consultation with a qualified specialist is recommended to determine the optimal treatment protocol.

The information was collected through numerous studies and analyses conducted over many years and is not intended for the diagnosis, treatment or prevention of any disease.

*All results are individual and depend on your health status